After Celta Vigo stunned Real Madrid at the Bernabeu last weekend, Barcelona are four points clear at the top of the La Liga standings. They host Osasuna on Saturday, so the pressure will likely be on Los Blancos when they travel to Vitoria on Sunday night.
The following is the predicted LaLiga line-up for matchday 16. All kick-off times are based on local time in Spain. Players in bold are those considered to have the highest chance of starting (80% or more).
LaLiga line-up predictions – Week 16
Friday 12 December 2025
21:00 – Real Sociedad vs Girona
Real Sociedad line-up predictions
Remira –Gomez, MartinZubeldia, Aramburu – Soler, Gorroxategi, B. Mendez – Barrenetxea, GuedesKubo (4-3-3)
Girona estimates the line-up
Gazzaniga – MorenoBlind, ReisA. Martinez – Martin, Witsel, Ounahi – Gil, Vanat, Tsygankov (4-3-3)

Saturday 13 December 2025
14:00 – Atlético Madrid vs Valencia
Predicted Atletico Madrid line-up
Cloud – Ruggeri, Language, The Norman, Mill – N. Gonzalez, BarriosCardoso, Simone – Sorloth, Alvarez (4-4-2)
Predicted Valencia line-up
With certificate – Style, PompadourComet, Foulquier, Korea – Danjuma, AshUgrinic, Rioja – Hard (5-4-1)
16:15 – Mallorca vs Elche
Mallorca estimates the line-up
Bergstrom – Mojicaplums, Valen, Maffeo – face maskMorlan – Virgil, More adventurousJoseph – Muriqi (4-2-3-1)
Elche estimates the line-up
Pen – Rice, AffengruberChust – Valera, FebruaryAguado, Nuñez, Fort – MirA. Rodriguez (3-5-2)
18:30 – Barcelona vs Osasuna
Prediction of Barcelona’s line-up
J. Garcia – BasketE. Garcia, Cubarsi, Trapped – PedriDe Jong – Raphinha, Fermin, Yamal – Ferran (4-2-3-1)
Predicted Osasuna line-up
Herrera – Breton, Row, Life, Rosier – Moncayola, Torro –Ruben Garcia, at all times, V. Muñoz – Raul Garcia (4-2-3-1)
21:00 – Getafe vs Espanyol
Getafe line-up predictions
Soria – Grass, DJENE, Duarte, IglesiasWoman – Martin, ArambarriJ. Muñoz – seed, Mayor (5-3-2)
Espanyol estimates the line-up
Dmitrovic – Romero, CabreraCalero, El Hilali – Exhibition, Gonzalez de ZarateLozano – MillaR. Fernandez, Jofre (4-3-3)

Sunday 14 December 2025
14:00 – Sevilla vs Real Oviedo
Sevilla estimates the line-up
Vlachodimos – Oso, Gudelj, Castrin, Carmona – Agoume, Mendi – Alfon, SowAlexis – Adam (4-2-3-1)
Real Oviedo line-up predictions
scandal – Thursday, Karmo, Costa, Vidal – Colombato, Dendoncker – plainQueen, Hassan – Rondon (4-2-3-1)
16:15 – Celta Vigo vs Athletic Club
Predicted line-up for Celta Vigo
They work – AlonsoStarfelt, M. Fernandez – Mingueza, Roman, Sotelo, Rueda – Zaragoza, Aspas – Iglesias (3-4-2-1)
Predicted Athletic Club line-up
Simon –Yuri, Parede, VivianGorosabel – palaceRuiz de Galareta – N. WilliamsSancet, Berenguer – Guruzeta (4-2-3-1)
18:30 – Levante vs Villarreal
Predicted Levante line-up
RYAN – Mr. SanchezMatturro, Cabello, that toljan – Brugui, Winner, Arriaga, C. Alvarez – Etta Eyong, Romero (4-4-2)
Predicted Villarreal line-up
Juniors – Cardona, Veiga, FoythNavarro – MillerCounselor, Heaven, Akhomach – A. PerezOluwaseyi (4-4-2)
21:00 – Alaves vs Real Madrid
Predicted Alaves line-up
heavy – Stop, Pacheco, clamp, Johnny – Ibañez, Blanco – Rebbach, D. Suarez, Calebe – Hiding (4-1-3-2)
Real Madrid line-up predictions
Court – Camavinga, Rudiger, Asencio, valveerde – Collar, Tchouameni, Bellingham – Vinicius, G. Garcia, Rodrygo (4-3-3)
Monday 15 December 2025
21:00 – Rayo Vallecano vs Real Betis
Rayo Vallecano estimated line-up
Battle – Chavarria, Mendy, Lejeune, Ratio – ValentinesCiss – A. Garcia, I. Palazon, F. Perez – Fruits (4-2-3-1)
Real Betis line-up predictions
P bartra, Ruibal – Roca, Fornal – Riquelme, Lo Celso, Anthony – C. Hernandez (4-2-3-1)
Mark is a freelance football writer based in Madrid, and editor of LaLigaExpert.com. He has covered LaLiga and European football since 2014.
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